The Genomics and Pharmacogenomics of Kawasaki Disease
نویسندگان
چکیده
Kawasaki Disease (KD) is an acute febrile systemic vasculitis that causes acquired cardiac disease in children in developed countries. It was first described by Kawasaki in 1967 [1] and is now known to occur worldwide. Importantly, KD is markedly more prevalent in Asian countries, including Japan, Korea, and Taiwan. Despite intensive research, several questions about KD remain unanswered, including the ones that follow: (i) What role is played by the genetic effect in disease susceptibility? (ii) What is the therapeutic mechanism of Intravenous Immunoglobulin (IVIG) for KD?
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